Pharmacogenomics Research Today is a free monthly online journal that collates and summarizes the latest research about Pharmacogenomics, including details on pharmacology, designer drugs, customized medicines.

Pharmacogenetic studies of epilepsy drugs: are we there yet?

Spurr NK

Genetics Research, GlaxoSmithKline R&D, New Medicines Research Centre, Stevenage, Herts, UK, SG1 2NY.

One of the mantras of scientists working in the field of pharmacogenetics is 'the right dose for the right patient'. A recent article has gone someway towards demonstrating that this goal can be achieved using genetic approaches. It is one of the first reports to show that a specific polymorphism can predict the maximum tolerated dose of two anti-epileptic drugs. However, further studies are necessary to validate these observations.

Published 8 May 2006 in Trends Genet, 22(5): 250-2.
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