Pharmacogenomics Research Today is a free monthly online journal that collates and summarizes the latest research about Pharmacogenomics, including details on pharmacology, designer drugs, customized medicines.

Pharmacogenetics: yeast lead the way.

Foss E, Bedalov A

Fred Hutchinson Cancer Research Center, Clinical Research Division, Seattle, Washington 98109, USA.

In this issue of Chemistry & Biology, Perlstein et al. use genetically diverse strains of yeast to study the genetic basis of differences in cellular responses to small molecules. Their results suggest that drug responses are regulated by a limited number of loci, and that this system can identify clusters of functionally similar molecules.

Published 26 April 2006 in Chem Biol, 13(3): 236-8.
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